Chlorproguanil−Dapsone−Artesunate versus Artemether−Lumefantrine: A Randomized, Double-Blind Phase III Trial in African Children and Adolescents with Uncomplicated Plasmodium falciparum Malaria

BACKGROUND: Chlorproguanil−dapsone−artesunate (CDA) was developed as an affordable, simple, fixed-dose artemisinin-based combination therapy for use in Africa. This trial was a randomized parallel-group, double-blind, double-dummy study to compare CDA and artemether−lumefantrine (AL) efficacy in unc...

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Main Authors: Premji, Zul, Umeh, Rich E., Owusu-Agyei, Seth, Esamai, Fabian, Ezedinachi, Emmanuel U., Oguche, Stephen, Borrmann, Steffen, Sowunmi, Akintunde, Duparc, Stephan, Kirby, Paula L., Pamba, Allan, Kellam, Lynda, Guiguemdé, Robert, Greenwood, Brian, Ward, Stephen A., Winstanley, Peter A.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2009
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2724683/
https://ncbi.nlm.nih.gov/pubmed/19690618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006682
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