Robust and Accurate Single Nucleotide Polymorphism Genotyping by Dynamic Allele-Specific Hybridization (DASH): Design Criteria and Assay Validation

We recently introduced a generic single nucleotide polymorphism (SNP) genotyping method, termed DASH (dynamic allele-specific hybridization), which entails dynamic tracking of probe (oligonucleotide) to target (PCR product) hybridization as reaction temperature is steadily increased. The reliability...

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Detalles Bibliográficos
Autores principales: Prince, Jonathan A., Feuk, Lars, Howell, W. Mathias, Jobs, Magnus, Emahazion, Tesfai, Blennow, Kaj, Brookes, Anthony J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2001
Materias:
Methods
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC311016/
https://ncbi.nlm.nih.gov/pubmed/11156624
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