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Specific PKC isoforms regulate LPS-stimulated iNOS induction in murine microglial cells
BACKGROUND: Excessive production of nitric oxide (NO) by inducible nitric oxide synthase (iNOS) in reactive microglia is a major contributor to initiation/exacerbation of inflammatory and degenerative neurological diseases. Previous studies have indicated that activation of protein kinase C (PKC) ca...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3110130/ https://ncbi.nlm.nih.gov/pubmed/21510893 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-8-38 |
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