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Two Functional Copies of the DGCR6 Gene Are Present on Human Chromosome 22q11 Due to a Duplication of an Ancestral Locus

The DGCR6 (DiGeorge critical region) gene encodes a putative protein with sequence similarity to gonadal (gdl), a Drosophila melanogaster gene of unknown function. We mapped the DGCR6 gene to chromosome 22q11 within a low copy repeat, termed sc11.1a, and identified a second copy of the gene, DGCR6L,...

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Detalhes bibliográficos
Main Authors: Edelmann, Lisa, Stankiewicz, Pavel, Spiteri, Elizabeth, Pandita, Raj K., Shaffer, Lisa, Lupski, James, Morrow, Bernice E.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC311013/
https://ncbi.nlm.nih.gov/pubmed/11157784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.143101
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