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Long-Range Comparison of Human and Mouse SCL Loci: Localized Regions of Sensitivity to Restriction Endonucleases Correspond Precisely with Peaks of Conserved Noncoding Sequences

Long-range comparative sequence analysis provides a powerful strategy for identifying conserved regulatory elements. The stem cell leukemia (SCL) gene encodes a bHLH transcription factor with a pivotal role in hemopoiesis and vasculogenesis, and it displays a highly conserved expression pattern. We...

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Publicado en:Genome Res
Autores principales: Göttgens, Berthold, Gilbert, James G.R., Barton, Linda M., Grafham, Darren, Rogers, Jane, Bentley, David R., Green, Anthony R.
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2001
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC311011/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11156618/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gr.153001
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