Long-Range Comparison of Human and Mouse SCL Loci: Localized Regions of Sensitivity to Restriction Endonucleases Correspond Precisely with Peaks of Conserved Noncoding Sequences

Long-range comparative sequence analysis provides a powerful strategy for identifying conserved regulatory elements. The stem cell leukemia (SCL) gene encodes a bHLH transcription factor with a pivotal role in hemopoiesis and vasculogenesis, and it displays a highly conserved expression pattern. We...

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Main Authors: Göttgens, Berthold, Gilbert, James G.R., Barton, Linda M., Grafham, Darren, Rogers, Jane, Bentley, David R., Green, Anthony R.
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2001
Teme:
Letter
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC311011/
https://ncbi.nlm.nih.gov/pubmed/11156618
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