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Myeloid-derived suppressor cells express the death receptor Fas and apoptose in response to T cell–expressed FasL

Myeloid-derived suppressor cells (MDSCs) inhibit adaptive and innate immunity and accumulate in the blood of persons with cancer, chronic inflammation, trauma, infection, and stress. Some of the factors inducing their accumulation are known; however, mechanisms regulating their turnover have not bee...

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Autori principali: Sinha, Pratima, Chornoguz, Olesya, Clements, Virginia K., Artemenko, Konstantin A., Zubarev, Roman A., Ostrand-Rosenberg, Suzanne
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3109712/
https://ncbi.nlm.nih.gov/pubmed/21450901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-11-321752
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