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Epithelial adhesion molecules can inhibit HIV-1–specific CD8(+) T-cell functions
Under persistent antigenic stimulation, virus-specific CD8(+) T cells become increasingly dysfunctional and up-regulate several inhibitory molecules such as killer lectin-like receptor G1 (KLRG1). Here, we demonstrate that HIV-1 antigen-specific T cells from subjects with chronic-progressive HIV-1 i...
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Main Authors: | , , , , , , , , , , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society of Hematology
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3109536/ https://ncbi.nlm.nih.gov/pubmed/21403126 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-12-321588 |
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