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Epithelial adhesion molecules can inhibit HIV-1–specific CD8(+) T-cell functions

Under persistent antigenic stimulation, virus-specific CD8(+) T cells become increasingly dysfunctional and up-regulate several inhibitory molecules such as killer lectin-like receptor G1 (KLRG1). Here, we demonstrate that HIV-1 antigen-specific T cells from subjects with chronic-progressive HIV-1 i...

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Detalhes bibliográficos
Main Authors: Streeck, Hendrik, Kwon, Douglas S., Pyo, Augustine, Flanders, Michael, Chevalier, Mathieu F., Law, Kenneth, Jülg, Boris, Trocha, Kasper, Jolin, Jonathan S., Anahtar, Melis N., Lian, Jeff, Toth, Ildiko, Brumme, Zabrina, Chang, J. Judy, Caron, Tyler, Rodig, Scott J., Milner, Danny A., Piechoka-Trocha, Alicja, Kaufmann, Daniel E., Walker, Bruce D., Altfeld, Marcus
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3109536/
https://ncbi.nlm.nih.gov/pubmed/21403126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-12-321588
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