Chemotherapy options in elderly and frail patients with metastatic colorectal cancer (MRC FOCUS2): an open-label, randomised factorial trial

BACKGROUND: Elderly and frail patients with cancer, although often treated with chemotherapy, are under-represented in clinical trials. We designed FOCUS2 to investigate reduced-dose chemotherapy options and to seek objective predictors of outcome in frail patients with advanced colorectal cancer. M...

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Autors principals: Seymour, Matthew T, Thompson, Lindsay C, Wasan, Harpreet S, Middleton, Gary, Brewster, Alison E, Shepherd, Stephen F, O'Mahony, M Sinead, Maughan, Timothy S, Parmar, Mahesh, Langley, Ruth E
Format: Artigo
Idioma:Inglês
Publicat: Lancet Publishing Group 2011
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3109515/
https://ncbi.nlm.nih.gov/pubmed/21570111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0140-6736(11)60399-1
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