A Method to Assess Linkage Disequilibrium between CNVs and SNPs Inside Copy Number Variable Regions

Since the discovery of the ubiquitous contribution of copy number variation to genetic variability, researchers have commonly used metrics such as r(2) to quantify linkage disequilibrium (LD) between copy number variants (CNVs) and single nucleotide polymorphisms (SNPs). However, these reports have...

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Detalhes bibliográficos
Main Authors: Wineinger, Nathan E., Pajewski, Nicholas M., Tiwari, Hemant K.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Research Foundation 2011
Assuntos:
Genetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3109359/
https://ncbi.nlm.nih.gov/pubmed/21660233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2011.00017
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