Insulin but Not Glucagon Gene is Silenced in Human Pancreas-Derived Mesenchymal Stem Cells

We previously characterized human islet-derived precursor cells (hIPCs) as a specific type of mesenchymal stem cell capable of differentiating to insulin (INS)- and glucagon (GCG)-expressing cells. However, during proliferative expansion, INS transcript becomes undetectable and then cannot be induce...

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Bibliografiske detaljer
Main Authors: Wilson, Leah M., Wong, Stephen H.K., Yu, Ningpu, Geras-Raaka, Elizabeth, Raaka, Bruce M., Gershengorn, Marvin C.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3109355/
https://ncbi.nlm.nih.gov/pubmed/19785038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.229
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