Icariin and its derivative, ICT, exert anti-inflammatory, anti-tumor effects, and modulate myeloid derived suppressive cells (MDSCs) functions

3, 5, 7-Trihydroxy-4'-methoxy-8-(3-hydroxy-3- methylbutyl)–flavone (ICT) is a novel derivative of Icariin (ICA), the major active ingredient of Herba Epimedii, a herb used in traditional Chinese and alternative medicine. We previously demonstrated its anti-inflammatory effect in murine innate i...

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Autori principali: Zhou, Junmin, Wu, Jinfeng, Chen, Xianghong, Fortenbery, Nicole, Eksioglu, Erika, Kodumudi, Krithika N., Epling- Burnette, Pearlie, Dong, Jingcheng, Djeu, Julie Y., Wei, Sheng
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3109231/
https://ncbi.nlm.nih.gov/pubmed/21244860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.intimp.2011.01.007
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