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Human Colonic Myofibroblasts Promote Expansion of CD4+ CD25(high) Foxp3+ Regulatory T Cells
BACKGROUND & AIMS: Regulatory T (Treg) cells (CD4+ CD25(high) FoxP3+) regulate mucosal tolerance; their adoptive transfer prevents or reduces symptoms of colitis in mouse models of inflammatory bowel disease (IBD). T-cell functions are regulated by mesenchymal cells. Colonic CD90(+) mesenchymal...
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| Huvudupphovsmän: | , , , , , , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2011
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3109194/ https://ncbi.nlm.nih.gov/pubmed/21376048 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2011.02.059 |
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