Dopamine-Derived Biological Reactive Intermediates and Protein Modifications: Implications for Parkinson’s Disease

Dopamine (DA) undergoes monoamine oxidase catalyzed oxidative deamination to 3,4-dihydroxyphenylacetaldehyde (DOPAL), which is metabolized primarily to 3,4-dihydroxyphenylacetic acid (DOPAC) via aldehyde dehydrogenase (ALDH). Previous studies demonstrated DOPAL to be neurotoxic, more so than DA and...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Jinsmaa, Yunden, Florang, Virginia R., Rees, Jennifer N., Mexas, Lydia M., Eckert, Laurie L., Allen, Erin M.G., Anderson, David G., Doorn, Jonathan A.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3109112/
https://ncbi.nlm.nih.gov/pubmed/21238438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2011.01.006
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares