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Motor Neuron Trophic Factors: Therapeutic Use in ALS?

The modest effects of neurotrophic factor (NTF) treatment on lifespan in both animal models and clinical studies of Amyotropic Lateral Sclerosis (ALS) may result from any one or combination of the four following explanations: 1.) NTFs block cell death in some physiological contexts but not in ALS; 2...

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Detalhes bibliográficos
Main Authors: Gould, Thomas W., Oppenheim, Ronald W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3109102/
https://ncbi.nlm.nih.gov/pubmed/20971133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainresrev.2010.10.003
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