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Gender Influences Cardiac Function in the mdx Model of Duchenne Cardiomyopathy

Aged mdx mice represent an important model for studying Duchenne cardiomyopathy. Herein we compared the cardiac phenotypes of 22-month-old male and female mdx mice. Surprisingly, only females displayed the characteristic cardiac dilation on pressure–volume loop analysis. Female mdx mice also exhibit...

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Bibliographic Details
Main Authors: Bostick, Brian, Yue, Yongping, Duan, Dongsheng
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3109082/
https://ncbi.nlm.nih.gov/pubmed/20878741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mus.21763
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