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Activation of AMP-Activated Protein Kinase Prevents Lipotoxicity in Retinal Pericytes

PURPOSE. The recent FIELD study demonstrated that the lipid-lowering agent fenofibrate significantly reduces the development and progression of diabetic retinopathy (DR). These results suggest that lipids may play a causal role in DR. They also suggest that AMP-activated protein kinase (AMPK) activa...

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Hlavní autoři: Cacicedo, José M., Benjachareonwong, Sunun, Chou, Eva, Yagihashi, Norito, Ruderman, Neil B., Ido, Yasuo
Médium: Artigo
Jazyk:Inglês
Vydáno: Association for Research in Vision and Ophthalmology, Inc. 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3109045/
https://ncbi.nlm.nih.gov/pubmed/21345991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.10-5784
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