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Topical Flagellin-Mediated Innate Defense against Candida albicans Keratitis

PURPOSE. This study was conducted to investigate whether flagellin, the sole ligand of Toll-like receptor-5 (TLR5), induces an innate defense that is sufficient to protect injured corneas from Candida albicans. METHODS. Scarified corneas of adult B6, TLR5(−/−), Camp(−/−) (cathelicidin-related antimi...

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Autors principals: Gao, Nan, Kumar, Ashok, Guo, Hui, Wu, Xinyi, Wheater, Michelle, Yu, Fu-Shin X.
Format: Artigo
Idioma:Inglês
Publicat: Association for Research in Vision and Ophthalmology, Inc. 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3109016/
https://ncbi.nlm.nih.gov/pubmed/21310913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.10-5928
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