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Differential Effects of Rapamycin on Rods and Cones During Light-Induced Stress in Albino Mice

PURPOSE. Autophagy is a lysosomal machinery-dependent process that catabolizes cellular components/organelles and proteins in an autophagic vacuole (AV)–dependent and –independent manner, respectively. Short-term exposure of the retina to bright light results in shortening of the outer segments, con...

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Main Authors: Kunchithapautham, Kannan, Coughlin, Beth, Lemasters, John J., Rohrer, Bärbel
Format: Artigo
Jezik:Inglês
Izdano: Association for Research in Vision and Ophthalmology, Inc. 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3109010/
https://ncbi.nlm.nih.gov/pubmed/21273550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.10-6278
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