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Deactivation of Signal Transducer and Activator of Transcription 3 Reverses Chemotherapeutics Resistance of Leukemia Cells via Down-Regulating P-gp
Multidrug resistance (MDR) caused by overexpression of p-glycoprotein is a major obstacle in chemotherapy of malignant cancer, which usually is characterized by constitutive activation of signal transducer and activator of transcription 3 (STAT3), but their relation between MDR and STAT3 remains unc...
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Hoofdauteurs: | , , , , |
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Formaat: | Artigo |
Taal: | Inglês |
Gepubliceerd in: |
Public Library of Science
2011
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Onderwerpen: | |
Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3108986/ https://ncbi.nlm.nih.gov/pubmed/21677772 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020965 |
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