Experimental Therapy of Ovarian Cancer with Synthetic Makaluvamine Analog: In Vitro and In Vivo Anticancer Activity and Molecular Mechanisms of Action

The present study was designed to determine the biological effects of novel marine alkaloid analog 7-(4-fluorobenzylamino)-1,3,4,8-tetrahydropyrrolo[4,3,2-de]quinolin-8(1H)-one (FBA-TPQ) on human ovarian cancer cells for its anti-tumor potential and the underlying mechanisms as a novel chemotherapeu...

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Main Authors: Chen, Tao, Xu, Yi, Guo, He, Liu, Yanling, Hu, Pingting, Yang, Xinying, Li, Xiaoguang, Ge, Shichao, Velu, Sadanandan E., Nadkarni, Dwayaja H., Wang, Wei, Zhang, Ruiwen, Wang, Hui
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2011
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3108973/
https://ncbi.nlm.nih.gov/pubmed/21673964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020729
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