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Defective angiogenesis in hypoplastic human fetal lungs correlates with nitric oxide synthase deficiency that occurs despite enhanced angiopoietin-2 and VEGF
Lung hypoplasia (LH) is a life-threatening congenital abnormality with various causes. It involves vascular bed underdevelopment with abnormal arterial muscularisation leading to pulmonary hypertension. Because underlying molecular changes are imperfectly known and sometimes controversial, we determ...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Physiological Society
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3108964/ https://ncbi.nlm.nih.gov/pubmed/20348277 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00333.2009 |
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