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l-Arginine Deprivation Regulates Cyclin D3 mRNA Stability in Human T Cells by Controlling HuR Expression

Myeloid-derived suppressor cells are a major mechanism of tumor-induced immune suppression in cancer. Arginase I-producing myeloid-derived suppressor cells deplete l-arginine (L-Arg) from the microenvironment, which arrests T cells in the G(0)–G(1) phase of the cell cycle. This cell cycle arrest cor...

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Detaylı Bibliyografya
Asıl Yazarlar: Rodriguez, Paulo C., Hernandez, Claudia P., Morrow, Kevin, Sierra, Rosa, Zabaleta, Jovanny, Wyczechowska, Dorota D., Ochoa, Augusto C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3108892/
https://ncbi.nlm.nih.gov/pubmed/20889542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1001224
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