Identification of inhibitors for putative malaria drug targets amongst novel antimalarial compounds

The efficacy of most marketed antimalarial drugs has been compromised by evolution of parasite resistance, underscoring an urgent need to find new drugs with new mechanisms of action. We have taken a high-throughput approach toward identifying novel antimalarial chemical inhibitors of prioritized dr...

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Detalhes bibliográficos
Main Authors: Crowther, Gregory J., Napuli, Alberto J., Gilligan, James H., Gagaring, Kerstin, Borboa, Rachel, Francek, Carolyn, Chen, Zhong, Dagostino, Eleanor F., Stockmyer, Justin B., Wang, Yu, Rodenbough, Philip P., Castaneda, Lisa J., Leibly, David J., Bhandari, Janhavi, Gelb, Michael H., Brinker, Achim, Engels, Ingo, Taylor, Jennifer, Chatterjee, Arnab K., Fantauzzi, Pascal, Glynne, Richard J., Van Voorhis, Wesley C., Kuhen, Kelli L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3108854/
https://ncbi.nlm.nih.gov/pubmed/20813141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molbiopara.2010.08.005
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