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Patterns of resistance development with integrase inhibitors in HIV

Raltegravir, the only integrase (IN) inhibitor approved for use in HIV therapy, has recently been licensed. Raltegravir inhibits HIV-1 replication by blocking the IN strand transfer reaction. More than 30 mutations have been associated with resistance to raltegravir and other IN strand transfer inhi...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Mbisa, Jean L, Martin, Supang A, Cane, Patricia A
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Dove Medical Press 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3108751/
https://ncbi.nlm.nih.gov/pubmed/21694910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IDR.S7775
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