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Patterns of resistance development with integrase inhibitors in HIV
Raltegravir, the only integrase (IN) inhibitor approved for use in HIV therapy, has recently been licensed. Raltegravir inhibits HIV-1 replication by blocking the IN strand transfer reaction. More than 30 mutations have been associated with resistance to raltegravir and other IN strand transfer inhi...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Dove Medical Press
2011
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3108751/ https://ncbi.nlm.nih.gov/pubmed/21694910 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IDR.S7775 |
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