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Glycogen Synthase Kinase 3 Beta (GSK3β) Phosphorylates the RNAase III Enzyme Drosha at S300 and S302

The canonical microRNA (miRNA) pathway commences with the enzymatic cleavage of the primary gene transcript (pri-miRNA) by the RNAase III enzyme Drosha in the nucleus into shorter pre-miRNA species that are subsequently exported to the cytoplasm for further processing into shorter, mature miRNA mole...

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Autors principals: Tang, Xiaoli, Li, Ming, Tucker, Lynne, Ramratnam, Bharat
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3108596/
https://ncbi.nlm.nih.gov/pubmed/21674040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020391
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