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Opposing cardiac effects of autoantibody activation of beta-adrenergic and M2 muscarinic receptors in cardiac-related diseases

BACKGROUND: Activating autoantibodies to β-adrenergic receptors (AAβ1/2AR) and M2 muscarinic receptors (AAM2R) have been reported in several cardiac diseases and may have pathophysiologic relevance. However, the interactions and relative effects of AAβ1AR, AAβ2AR and AAM2R on contractile function ha...

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Detalhes bibliográficos
Main Authors: Stavrakis, Stavros, Kem, David C., Patterson, Eugene, Lozano, Pedro, Huang, Shijun, Szabo, Bela, Cunningham, Madeleine W., Lazzara, Ralph, Yu, Xichun
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3108570/
https://ncbi.nlm.nih.gov/pubmed/20053466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijcard.2009.11.025
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