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THE PLECKSTRIN HOMOLOGY DOMAIN IN THE SKAP55 ADAPTER PROTEIN DEFINES THE ABILITY OF THE ADAPTER PROTEIN ADAP TO REGULATE INTEGRIN FUNCTION AND NF-κB ACTIVATION
Adhesion and degranulation-promoting adapter protein (ADAP) is a multi-functional hematopoietic adapter protein that regulates TCR-dependent increases in both integrin function and activation of the NF-κB transcription factor. Activation of integrin function requires both ADAP and the ADAP-associate...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3108501/ https://ncbi.nlm.nih.gov/pubmed/21525391 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1002950 |
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