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Distinct Regulation of Integrin-Dependent T Cell Conjugate Formation and NF-κB activation by the Adapter Protein ADAP

Following TCR stimulation, T cells utilize the hematopoietic specific adhesion and degranulation promoting adapter protein (ADAP) to control both integrin adhesive function and NF-κB transcription factor activation. We have investigated the molecular basis by which ADAP controls these events in prim...

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Detalhes bibliográficos
Main Authors: Burbach, Brandon J., Srivastava, Rupa, Medeiros, Ricardo B., O'Gorman, William E., Peterson, Erik J., Shimizu, Yoji
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2593878/
https://ncbi.nlm.nih.gov/pubmed/18802088
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