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Abnormal colonic motility in mice overexpressing human wild-type α-synuclein
The presynaptic protein α-synuclein (αSyn) has been implicated in both familial and sporadic forms of Parkinson’s disease. We examined whether human αSyn-overexpressing mice under Thy1 promoter (Thy1-αSyn) display alterations of colonic function. Basal fecal output was decreased in Thy1-αSyn mice fe...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3108489/ https://ncbi.nlm.nih.gov/pubmed/18463504 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/WNR.0b013e3282ffda5e |
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