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Early and Progressive Sensorimotor Anomalies in Mice Overexpressing Wild-Type Human α-Synuclein

Accumulation of α-synuclein in brain is a hallmark of synucleinopathies, neurodegenerative diseases that include Parkinson's disease. Mice overexpressing α-synuclein under the Thy-1 promoter (ASO) show abnormal accumulation of α-synuclein in cortical and subcortical regions of the brain, includ...

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書誌詳細
出版年:J Neurosci
主要な著者: Fleming, Sheila M., Salcedo, Jonathan, Fernagut, Pierre-Olivier, Rockenstein, Edward, Masliah, Eliezer, Levine, Michael S., Chesselet, Marie-Françoise
フォーマット: Artigo
言語:Inglês
出版事項: Society for Neuroscience 2004
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6730110/
https://ncbi.nlm.nih.gov/pubmed/15496679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3080-04.2004
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