A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium

The number and volume of cells in the blood affect a wide range of disorders including cancer and cardiovascular, metabolic, infectious and immune conditions. We consider here the genetic variation in eight clinically relevant hematological parameters, including hemoglobin levels, red and white bloo...

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Detalhes bibliográficos
Main Authors: Soranzo, Nicole, Spector, Tim D, Mangino, Massimo, Kühnel, Brigitte, Rendon, Augusto, Teumer, Alexander, Willenborg, Christina, Wright, Benjamin, Chen, Li, Li, Mingyao, Salo, Perttu, Voight, Benjamin F, Burns, Philippa, Laskowski, Roman A, Xue, Yali, Menzel, Stephan, Altshuler, David, Bradley, John R, Bumpstead, Suzannah, Burnett, Mary-Susan, Devaney, Joseph, Döring, Angela, Elosua, Roberto, Epstein, Stephen, Erber, Wendy, Falchi, Mario, Garner, Stephen F, Ghori, Mohammed J R, Goodall, Alison H, Gwilliam, Rhian, Hakonarson, Hakon H, Hall, Alistair S, Hammond, Naomi, Hengstenberg, Christian, Illig, Thomas, König, Inke R, Knouff, Christopher W, McPherson, Ruth, Melander, Olle, Mooser, Vincent, Nauck, Matthias, Nieminen, Markku S, O’Donnell, Christopher J, Peltonen, Leena, Potter, Simon C, Prokisch, Holger, Rader, Daniel J, Rice, Catherine M, Roberts, Robert, Salomaa, Veikko, Sambrook, Jennifer, Schreiber, Stefan, Schunkert, Heribert, Schwartz, Stephen M, Serbanovic-Canic, Jovana, Sinisalo, Juha, Siscovick, David S., Stark, Klaus, Surakka, Ida, Stephens, Jonathan, Thompson, John R, Völker, Uwe, Völzke, Henry, Watkins, Nicholas A, Wells, George A, Wichmann, H-Erich, Van Heel, David A, Tyler-Smith, Chris, Thein, Swee Lay, Kathiresan, Sekar, Perola, Markus, Reilly, Muredach P, Stewart, Alexandre F R, Erdmann, Jeanette, Samani, Nilesh J, Meisinger, Christa, Greinacher, Andreas, Deloukas, Panos, Ouwehand, Willem H, Gieger, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3108459/
https://ncbi.nlm.nih.gov/pubmed/19820697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.467
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