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An expanded sequence context model broadly explains variability in polymorphism levels across the human genome
The rate of single nucleotide polymorphism varies substantially across the human genome and fundamentally influences evolution and incidence of genetic disease. Previous studies have only considered the immediate flanking nucleotides around a polymorphic site –the site’s trinucleotide sequence conte...
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| Udgivet i: | Nat Genet |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4811712/ https://ncbi.nlm.nih.gov/pubmed/26878723 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.3511 |
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