Silibinin induces apoptosis via calpain-dependent AIF nuclear translocation in U87MG human glioma cell death

BACKGROUND: Silibinin, a natural polyphenolic flavonoid, has been reported to induce cell death in various cancer cell types. However, the molecular mechanism is not clearly defined. Our previous study showed that silibinin induces glioma cell death and its effect was effectively prevented by calpai...

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Detalhes bibliográficos
Main Authors: Jeong, Ji C, Shin, Won Y, Kim, Thae H, Kwon, Chae H, Kim, Jae H, Kim, Yong K, Kim, Ki H
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3108340/
https://ncbi.nlm.nih.gov/pubmed/21501525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-9966-30-44
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