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Silencing Survivin Splice Variant 2B Leads to Antitumor Activity in Taxane-Resistant Ovarian Cancer
PURPOSE: To study the role of survivin and its splice variants in taxane-resistant ovarian cancer. EXPERIMENTAL DESIGN: We assessed the messenger RNA levels of survivin splice variants in ovarian cancer cell lines and ovarian tumor samples. Small-interference RNAs (siRNAs) targeting survivin were de...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3108184/ https://ncbi.nlm.nih.gov/pubmed/21512144 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-11-0233 |
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