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Linkage Disequilibrium and Physical Mapping of Pas1 in Mice

By using linkage disequilibrium (LD) analysis in 21 strains of known susceptibility to lung cancer and by assembling a YAC contig, we mapped to a ∼1.5-Mb region on distal mouse chromosome 6 the Pas1 locus, the major determinant of lung cancer predisposition in mice. Our results, on the basis of hapl...

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Publicat a:Genome Res
Autors principals: Manenti, Giacomo, Stafford, Amanda, De Gregorio, Laura, Gariboldi, Manuela, Falvella, F. Stefania, Avner, Philip, Dragani, Tommaso A.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 1999
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC310797/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10413402/
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