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Linkage Disequilibrium and Physical Mapping of Pas1 in Mice

By using linkage disequilibrium (LD) analysis in 21 strains of known susceptibility to lung cancer and by assembling a YAC contig, we mapped to a ∼1.5-Mb region on distal mouse chromosome 6 the Pas1 locus, the major determinant of lung cancer predisposition in mice. Our results, on the basis of hapl...

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Huvudupphovsmän: Manenti, Giacomo, Stafford, Amanda, De Gregorio, Laura, Gariboldi, Manuela, Falvella, F. Stefania, Avner, Philip, Dragani, Tommaso A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Cold Spring Harbor Laboratory Press 1999
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC310797/
https://ncbi.nlm.nih.gov/pubmed/10413402
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