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CYLD Inhibits Tumorigenesis and Metastasis by Blocking JNK/AP1 Signaling at Multiple Levels

CYLD has been recognized as a tumor suppressor due to its dominant genetic linkage to multiple types of epidermal tumors and a range of other cancers. The molecular mechanisms governing CYLD control of skin cancer are still unclear. Here, we demonstrated that K14-driven epidermal expression of a pat...

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Hlavní autoři: de Marval, Paula Miliani, Lutfeali, Shazia, Jin, Jane Y., Leshin, Benjamin, Selim, M. Angelica, Zhang, Jennifer Y.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3107906/
https://ncbi.nlm.nih.gov/pubmed/21478324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-10-0360
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