The role of KRAS rs61764370 in invasive epithelial ovarian cancer: implications for clinical testing

PURPOSE: An assay for the single nucleotide polymorphism (SNP) rs61764370 has recently been commercially marketed as a clinical test to aid ovarian cancer risk evaluation in women with family histories of the disease. rs67164370 is in a 3′UTR miRNA binding site of the KRAS oncogene, and is a candida...

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Main Authors: Pharoah, Paul D. P., Palmieri, Rachel T., Ramus, Susan J., Gayther, Simon A., Andrulis, Irene L., Anton-Culver, Hoda, Antonenkova, Natalia, Antoniou, Antonis C., Beattie, Mary S., Beckmann, Matthias W., Birrer, Michael J., Bogdanova, Natalia, Bolton, Kelly L., Brewster, Wendy, Brooks-Wilson, Angela, Brown, Robert, Butzow, Ralf, Caldes, Trinidad, Caligo, Maria Adelaide, Campbell, Ian, Chang-Claude, Jenny, Chen, Y. Ann, Chenevix-Trench, Georgia, Cook, Linda S., Couch, Fergus J., Cramer, Daniel W., Cunningham, Julie M., Despierre, Evelyn, Doherty, Jennifer A., Dörk, Thilo, Dürst, Matthias, Eccles, Diana M., Ekici, Arif B., Fasching, Peter A., de Fazio, Anna, Fenstermacher, David A., Flanagan, James M., Fridley, Brooke L., Friedman, Eitan, Gao, Bo, Gentry-Maharaj, Aleksandra, Godwin, Andrew K., Goode, Ellen L., Goodman, Marc T., Gross, Jenny, Hansen, Thomas V. O., Harnett, Paul, Heikkinen, Tuomas, Hein, Rebecca, Høgdall, Claus, Høgdall, Estrid, Iversen, Edwin S., Jakubowska, Anna, Johnatty, Sharon E., Karlan, Beth Y., Kauff, Noah D., Kaye, Stanley B., Kelemen, Linda E., Kiemeney, Lambertus A., Kjaer, Susanne Krüger, Lambrechts, Diether, LaPolla, James P., Lázaro, Conxi, Le, Nhu D., Leminen, Arto, Leunen, Karin, Levine, Douglas A., Lu, Yi, Lundvall, Lene, Macgregor, Stuart, Marees, Tamara, Massuger, Leon F., McLaughlin, John R., Menon, Usha, Montagna, Marco, Moysich, Kirsten B., Narod, Steven A., Nathanson, Katherine L., Nedergaard, Lotte, Ness, Roberta B., Nevanlinna, Heli, Nickels, Stefan, Osorio, Ana, Paul, Jim, Pearce, Celeste Leigh, Phelan, Catherine M., Pike, Malcolm C., Radice, Paolo, Rossing, Mary Anne, Schildkraut, Joellen M., Sellers, Thomas A., Singer, Christian F., Song, Honglin, Stram, Daniel O., Sutphen, Rebecca, Terry, Kathryn L., Tsai, Ya-Yu, van Altena, Anne M., Vergote, Ignace, Vierkant, Robert A., Vitonis, Allison F., Walsh, Christine, Wang-Gohrke, Shan, Wappenschmidt, Barbara, Wu, Anna H., Ziogas, Argyrios, Berchuck, Andrew, Risch, Harvey A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3107901/
https://ncbi.nlm.nih.gov/pubmed/21385923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-10-3405
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