Prevention of Metastasis in a 4T1 Murine Breast Cancer Model by Doxorubicin Carried by Folate Conjugated pH Sensitive Polymeric Micelles

This study primarily focused on the anti-metastatic activity of doxorubicin (DOX) loaded in a pH-sensitive mixed polymeric micelle formed from two block polymers: poly(L-lactide) (PLLA) (Mn 3000)-b-poly(ethylene glycol) (PEG) (Mn 2000)-folate and poly(L-histidine) (PHis) (Mn 4700)-b-PEG (Mn 2000). T...

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Main Authors: Gao, Zhong-Gao, Tian, Li, Hu, Jun, Park, In-Suh, Bae, You Han
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3107897/
https://ncbi.nlm.nih.gov/pubmed/21295088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2011.01.021
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