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In vivo evaluation of doxorubicin-loaded polymeric micelles targeting folate receptors and early endosomal pH in drug-resistant ovarian cancer
The second generation of pH-sensitive micelles composed of poly((L)-histidine-co-(L)-phenlyalanine (16 mol%))(MW: 5K)-b-PEG(MW: 2K) and poly((L)-lactic acid)(MW: 3K)-b-PEG(MW: 2K)-folate (80/20 wt/wt%) was previously optimized by physicochemical and in vitro tests for both folate receptor and early...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2760434/ https://ncbi.nlm.nih.gov/pubmed/19507896 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp900021q |
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