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Behavioral effects of clozapine: Involvement of trace amine pathways in C. elegans and M. musculus

Clozapine is an antipsychotic medication with superior efficacy in treatment-refractory schizophrenia. The molecular basis of clozapine’s therapeutic profile is not well understood. We studied behavioral effects of clozapine in Caenorhabditis elegans to identify novel pathways that modulate clozapin...

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Autors principals: Karmacharya, Rakesh, Lynn, Spencer K., Demarco, Sarah, Ortiz, Angelica, Wang, Xin, Lundy, Miriam Y., Xie, Zhihua, Cohen, Bruce M., Miller, Gregory M., Buttner, Edgar A.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3107707/
https://ncbi.nlm.nih.gov/pubmed/21529784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2011.04.010
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