Gα(o/i)-stimulated proteosomal degradation of RGS20: A mechanism for temporal integration of G(s) and G(i) pathways

The G(s) and G(i) pathways interact to control the levels of intracellular cAMP. Although coincident signaling through G(s) and G(i)-coupled receptors can attenuate G(s)-stimulated cAMP levels, it is not known if prior activation of the G(i) pathway can affect signaling by G(s)-coupled receptors. We...

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Hlavní autoři: Pagano, Mario, Jordan, J. Dedrick, Neves, Susana R., Nguyen, Tracy, Iyengar, Ravi
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3107604/
https://ncbi.nlm.nih.gov/pubmed/18407463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2008.02.008
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