Mechanism of AMPK Suppression of LXR-dependent Srebp-1c Transcription

Activation of AMP-activated protein kinase (AMPK) inhibits hepatic fatty acid synthesis by suppressing sterol regulatory element-binding protein (SREBP)-1c, a master regulator of hepatic lipogenic gene expression. Using a model cell line rat hepatoma McA-RH7777 (CRL-1601) that mimics the behavior of...

Full description

Saved in:
Bibliographic Details
Main Authors: Yap, Fuichi, Craddock, Lauren, Yang, Jian
Format: Artigo
Language:Inglês
Published: Ivyspring International Publisher 2011
Subjects:
Short Research Communication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3107472/
https://ncbi.nlm.nih.gov/pubmed/21647332
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items