Histone Methyltransferase KMT1A Restrains Entry of Alveolar Rhabdomyosarcoma Cells into a Myogenic Differentiated State

Alveolar rhabdomyosarcoma (ARMS) is an aggressive pediatric muscle cancer which arrested during the process of skeletal muscle differentiation. In muscle myoblast cells, ectopic expression of the histone H3 lysine 9 (H3K9) methytransferase KMT1A blocks differentiation by repressing a myogenic gene e...

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Bibliographic Details
Main Authors: Lee, Min-Hyung, Jothi, Mathivanan, Gudkov, Andrei V., Mal, Asoke K.
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3107367/
https://ncbi.nlm.nih.gov/pubmed/21493592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-3358
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