Rescue of Targeted Regions of Mammalian Chromosomes by in Vivo Recombination in Yeast

In contrast to other animal cell lines, the chicken pre-B cell lymphoma line, DT40, exhibits a high level of homologous recombination, which can be exploited to generate site-specific alterations in defined target genes or regions. In addition, the ability to generate human/chicken monochromosomal h...

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Détails bibliographiques

Publié dans:	Genome Res
Auteurs principaux:	Kouprina, Natalya, Kawamoto, Kensaku, Barrett, J. Carl, Larionov, Vladimir, Koi, Minoru
Format:	Artigo
Langue:	Inglês
Publié:	Cold Spring Harbor Laboratory Press 1998
Sujets:	Genome Methods
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC310736/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9647640/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gr.8.6.666
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