Aldehyde dehydrogenase in combination with CD133 defines angiogenic ovarian cancer stem cells that portend poor patient survival

Markers that reliably identify cancer stem cells (CSC) in ovarian cancer could assist prognosis and improve strategies for therapy. CD133 is a reported marker of ovarian CSC. Aldehyde dehydrogenase (ALDH) activity is a reported CSC marker in several solid tumors but it has not been studied in ovaria...

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Huvudupphovsmän: Silva, Ines A., Bai, Shoumei, McLean, Karen, Yang, Kun, Griffith, Kent, Thomas, Dafydd, Ginestier, Christophe, Johnston, Carolyn, Kueck, Angela, Reynolds, R. Kevin, Wicha, Max S., Buckanovich, Ronald J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3107359/
https://ncbi.nlm.nih.gov/pubmed/21498635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-3175
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