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Counting individual DNA molecules by the stochastic attachment of diverse labels
We implement a unique strategy for single molecule counting termed stochastic labeling, where random attachment of a diverse set of labels converts a population of identical DNA molecules into a population of distinct DNA molecules suitable for threshold detection. The conceptual framework for stoch...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3107322/ https://ncbi.nlm.nih.gov/pubmed/21562209 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1017621108 |
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