Phosphorylation state of a Tob/BTG protein, FOG-3, regulates initiation and maintenance of the Caenorhabditis elegans sperm fate program

FOG-3, the single Caenorhabditis elegans Tob/BTG protein, directs germ cells to adopt the sperm fate at the expense of oogenesis. Importantly, FOG-3 activity must be maintained for the continued production of sperm that is typical of the male sex. Vertebrate Tob proteins have antiproliferative activ...

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Bibliographic Details
Main Authors: Lee, Myon-Hee, Won Kim, Kyung, Morgan, Clinton T., Morgan, Dyan E., Kimble, Judith
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2011
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3107262/
https://ncbi.nlm.nih.gov/pubmed/21571637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1106027108
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